Pharmacology MCQ

Side effects of Aspirin 1) Reye syndrome in children 2) Stomach ulceration / bleeding 3) Tinnitus at high doses 4) Bronchospasm, worsening asthma Bleeding risk higher in patients that are taking: 5) An NSAID 6)  Alcohol 7) Blood thinners Risk higher in older patients .

drug of choice 1. Enuresis      = imipramine 2. Rheumatic fever =penicillin 3. Paracetamol poisoning- :- - acetyl cysteine 4. acute bronchial- asthma :- salbutamol 5. acute gout :- NSAIDS 6. acute hyperkalemia:- calcium gluconate 7. severe DIGITALIS toxicity :-DIGIBIND 8. acute migraine :- sumatriptan 9. cheese reaction :- phentolamine 10. atropine poisoning :- physostigmine 11. cyanide poisoning :- amyl nitrite 12. benzodiazepine poisoning:- flumazenil 13. cholera :- tetracycline 14. KALA-AZAR :- lipozomal amphotericin- B 15. iron poisoning :- desferrioxamine  16. MRSA :- vancomycin 17. VRSA :- LINEZOLID 18. warfarin overdose :- vitamin-K (NIPER- 2009) 19. OCD -  fluoxetine 20. alcohol poisoning :- fomepizole 21. epilepsy in pregnency :- phenobarbitone 22. anaphylactic shock :- Adrenaline 23. Malaria in Pregnancy-Chloroquine 24. Whooping Cough or Perteusis- Erythromycin 25. Kawasaki disease-IV Ig 26. Heparin Overdose-Protamine 27. Ha...

Essential drugs’ are:? A. Life saving drugs B. Drugs that meet the priority health care needs of the population C. Drugs that must be present in the emergency bag of a doctor D. Drugs that are listed in the pharmacopoia of a country 2) An 'orphan drug' is: A. A very cheap drug B. A drug which has no therapeutic use C. A drug needed for treatment or prevention of a rare disease D. A drug which acts on Orphanin receptors 3 )Drug administered through the following route is most likely to be subjected to first-pass metabolism:? A. Oral B. Sublingual C. Subcutaneous D. Rectal 1 B        2 C    3 A

➖➖➖➖➖➖➖➖➖➖➖➖   New Drugs: 2017 - Till August ➖➖➖➖➖➖➖➖➖➖➖➖ 1. Avelumab: Anti PD1 (Programmed Death ligand 1 Ab approved for metastatic Merkel cell carcinoma. 2. Dupilumab: Anti IL 4 receptor alpha antibody approved for treatment of atopic dermatitis. 3. Brodalumab: Anti IL 17 A receptor Ab approved for treatment of plaque psoriasis. 4. Plecanatide: Guanylate cyclase c stimulator approved for treatment of chronic idiopathic constipation. It increases cyc GMP, which stimulates CTFR ( Cystic Fibrosis Transmembrane Regulator), which increases Cl ion secretion in to gut. 5. Naldenedine: Opioid antagonist approved for treatment of opioid induced constipation. 6. Telotristat: Tryptophan hydroxylase inibitor approved for treatment of carcinoid syndrome. It inhibits serotonin synthesis. 7. Midostaurin: Multikinase inhibitor approved for treatment of • AML: Along with TOC (Cytarabine + Daunorobicin) in FLT3 mutation positive cases. • Aggressive systemic mastocytosis • Syst...

Q.All of the following are true about methanol poisoing except? A. Fomepizole is a competitive inhibitor of aldehyde dehydrogenase B. Toxic level of methanol is 1.25 gm/kg body wt C. Formic acid is mainly responsible for toxicity D. Methanol causes obscured snowy vision